Evaluation of the effect of Nigella sativa oil on the outcome of missed abortion in women: A randomized double‐blind clinical trial

Autor: Belgheis Mohammadi, Leila Nazari Robati, Zeinab Tavakol, Mina Movahhed
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Health Science Reports, Vol 7, Iss 4, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.2029
Popis: Abstract Background and Aim Due to the concern about the side effects of chemical drugs and their ineffectiveness, the use of natural compounds as alternatives or complementary therapies has received increasing attention. The purpose of this study was to investigate the effect of Nigella sativa oil on the outcome of missed abortion. Methods In this double‐blind clinical trial, 70 nulliparous pregnant women referred to Hajar Hospital and Imam Ali clinics of Shahrekord and had missed abortion before the 12‐week gestational age were selected and randomly divided into two interventions and control groups. The intervention group received 5 g of Nigella sativa oil alone daily for up to 3 days and the control group received a placebo. In case of nonresponse, 3 days after the last dose of medication or placebo, 800 μg of misoprostol (vaginal) were used. Data were analyzed by SPSS software. The chi‐square test, Fisher's exact test, independent t‐test and paired t‐test were used for analytical statistics. Results According to the results, 18 cases (51.4%) in the intervention group and seven cases (20%) in the control group showed complete evacuation of uterine contents which had a significant difference (p
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