Development and evaluation of a novel dietary bisphenol A (BPA) exposure risk tool

Autor: Jennifer C. Hartle, Roy S. Zawadzki, Joseph Rigdon, Juleen Lam, Christopher D. Gardner
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Nutrition, Vol 8, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2055-0928
DOI: 10.1186/s40795-022-00634-4
Popis: Abstract Background Exposure to endocrine disrupting chemicals such as bisphenol A (BPA) is primarily from the diet through canned foods. Characterizing dietary exposures can be conducted through biomonitoring and dietary surveys; however, these methods can be time-consuming and challenging to implement. Methods We developed a novel dietary exposure risk questionnaire to evaluate BPA exposure and compared these results to 24-hr dietary recall data from participants (n = 404) of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) study, a dietary clinical trial, to validate questionnaire responses. High BPA exposure foods were identified from the dietary recalls and used to estimate BPA exposure. Linear regression models estimated the association between exposure to BPA and questionnaire responses. A composite risk score was developed to summarize questionnaire responses. Results In questionnaire data, 65% of participants ate canned food every week. A composite exposure score validated that the dietary exposure risk questionnaire captured increasing BPA exposure. In the linear regression models, utilizing questionnaire responses vs. 24-hr dietary recall data, participants eating canned foods 1–2 times/week (vs. never) consumed 0.78 more servings (p
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