Assessment of Trace Metal Disturbances in Healthcare Workers Exposed to Low Dose Ionizing Radiations in a Tertiary Care Hospital

Autor: Ahsan Ahmad Ghauri, Muhammad Usman Munir, Zujaja Hina Haroon, Muhammad Aamir, Muhammad Babar Khan, Sobia Irum Kirmani
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 73, Iss 5 (2023)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
DOI: 10.51253/pafmj.v73i5.7753
Popis: Objective: To determine the effects of ionizing radiations on trace metal levels in healthcare workers exposed to occupational radiation in a tertiary care health facility. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Chemical Pathology & Endocrinology, Armed Forces Institute of Pathology, Rawalpindi Pakistan, in collaboration with the Department of Radiology, Combined Military Hospital, Rawalpindi Pakistan, from Apr to Oct 2021. Methodology: Healthcare workers (n=45) exposed to occupational radiations were compared with an equal number of Controls in a tertiary care health facility for their trace metal levels. An atomic absorption spectrophotometer (AAS) was used to measure serum zinc (Zn) and copper (Cu) levels. A calorimetric technique was used to measure serum iron (Fe) levels. Results: Mean serum Copper (9.54±2.52 µmol/l) and Zinc (11.78±1.90 µmol/l) concentrations of the Risk-Group were significantly lower than their respective Control-Groups (Copper: 14.76±3.13 µmol/l and Zinc: 14.67±3.01 µmol/l). At the same time, mean serum Iron levels in the Exposed-Group (17.55±3.88 µmol/l) were significantly (p
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