Transmucosal Absorption Enhancers in the Drug Delivery Field

Autor:	Sam Maher, Luca Casettari, Lisbeth Illum
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	permeation enhancers absorption modifying excipients oral delivery nasal delivery ocular delivery vaginal delivery transmucosal permeation Pharmacy and materia medica RS1-441
Zdroj:	Pharmaceutics, Vol 11, Iss 7, p 339 (2019)
Druh dokumentu:	article
ISSN:	1999-4923
DOI:	10.3390/pharmaceutics11070339
Popis:	Drug delivery systems that safely and consistently improve transport of poorly absorbed compounds across epithelial barriers are highly sought within the drug delivery field. The use of chemical permeation enhancers is one of the simplest and widely tested approaches to improve transmucosal permeability via oral, nasal, buccal, ocular and pulmonary routes. To date, only a small number of permeation enhancers have progressed to clinical trials, and only one product that includes a permeation enhancer has reached the pharmaceutical market. This editorial is an introduction to the special issue entitled Transmucosal Absorption Enhancers in the Drug Delivery Field (https://www.mdpi.com/journal/pharmaceutics/special_issues/transmucosal_absorption_enhancers). The guest editors outline the scope of the issue, reflect on the results and the conclusions of the 19 articles published in the issue and provide an outlook on the use of permeation enhancers in the drug delivery field.
Databáze:	Directory of Open Access Journals
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