Comparsion of central aortic pressure to brachial artery pressure in hypertensive patients on drug treatment: An observational study

Autor: Bilal Ahmad Baba, Pandit Tafiq Johan, Jagdish C. Mohan
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Indian Heart Journal, Vol 70, Iss , Pp S208-S212 (2018)
Druh dokumentu: article
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2018.10.418
Popis: Background: High brachial blood pressure (BP) is an important cardiovascular risk factor. However major differences in central systolic BP can occur among people with similar brachial systolic BP. It is known that central aortic pressure responses to antihypertensive therapy can differ substantially from brachial BP responses, such that true treatment effects cannot be gauged from conventional brachial BP. Objective: The purpose of this study was to examine if adequate control of brachial BP was concordant with central BP control in treated hypertensive subjects. Methods: Non-invasive acquisition of brachial and central pressures and wave forms was obtained from 100 subjects with systemic arterial hypertension on drug therapy and 50 healthy individuals. After all necessary precautions according to the guidelines, brachial and central pressures and wave forms were measured 3 times at 5 min intervals using an upper arm cuff (AGEDIO K900 HDP Stolberg, Germany). The mean of the last two measurements of each was recorded as representative of brachial and central aortic pressures and wave forms. Results: In 45 of 50 healthy subjects with normotension (41 male, 9 female, mean age 38 years), central systolic BP was 140/90 mmHg and central systolic BP > 120 mmHg). Ninety-one patients had controlled hypertension as estimated by brachial BP of whom, 37 patients had uncontrolled central BP (systolic BP > 120 mmHg). Thus, brachial BP estimation over-estimated control of hypertension in 41% patients (p
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