Impact of home confinement due to the COVID‐19 outbreak on vitamin D levels and trends among children with pneumonia aged 1–35 months

Autor: Xueer Wang, Jianchuan Chen, Runting Huang, Ting Gong, Lin Zhu, Tingting Luo, Shu Yang, Li Yan, Gang Geng, Jihong Dai, Xiaoqiang Li, Daiyin Tian
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Pediatric Discovery, Vol 2, Iss 1, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2835-5598
2835-558X
DOI: 10.1002/pdi3.41
Popis: Abstract Vitamin D plays a vital role in immunity and is related to susceptibility and the severity of pneumonia. The home confinement caused by the novel coronavirus disease (COVID‐19) decreased sunlight exposure derived from outdoor activities in children, thereby possibly exerting an influence on 25‐hydroxyvitamin D [25(OH)D] levels. The aim of this study is to quantify vitamin D level changes and trends among infants and toddlers with community‐acquired pneumonia (CAP) during and post the home confinement period. This study included children who were hospitalized in the respiratory department of the Children's Hospital of Chongqing Medical University with CAP between February 1 and July 31 from 2020 to 2022 (N = 397). We used propensity score matching to control the confounding bias. The levels and trends of the children's serum 25(OH)D concentrations overall and by age groups were compared between the different periods. The serum 25(OH)D concentration during the home confinement period was lower (p
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