| Autor: |
Kathryn V. Papp, Aubryn Samaroo, Hsiang‐Chin Chou, Rachel Buckley, Olivia R. Schneider, Stephanie Hsieh, Daniel Soberanes, Yakeel Quiroz, Michael Properzi, Aaron Schultz, Iván García‐Magariño, Gad A. Marshall, Jane G. Burke, Raya Kumar, Noah Snyder, Keith Johnson, Dorene M. Rentz, Reisa A. Sperling, Rebecca E. Amariglio |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2352-8729 |
| DOI: |
10.1002/dad2.12243 |
| Popis: |
Abstract Introduction Unsupervised digital cognitive testing is an appealing means to capture subtle cognitive decline in preclinical Alzheimer's disease (AD). Here, we describe development, feasibility, and validity of the Boston Remote Assessment for Neurocognitive Health (BRANCH) against in‐person cognitive testing and amyloid/tau burden. Methods BRANCH is web‐based, self‐guided, and assesses memory processes vulnerable in AD. Clinically normal participants (n = 234; aged 50–89) completed BRANCH; a subset underwent in‐person cognitive testing and positron emission tomography imaging. Mean accuracy across BRANCH tests (Categories, Face‐Name‐Occupation, Groceries, Signs) was calculated. Results BRANCH was feasible to complete on participants’ own devices (primarily smartphones). Technical difficulties and invalid/unusable data were infrequent. BRANCH psychometric properties were sound, including good retest reliability. BRANCH was correlated with in‐person cognitive testing (r = 0.617, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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