Value of hematological parameters for predicting patients with severe coronavirus disease 2019: a real-world cohort from Morocco
| Autor: | Ali Azghar, Mohammed Bensalah, Abdelilah Berhili, Mounia Slaoui, Boutaina Mouhoub, Imane El Mezgueldi, Oumaima Nassiri, Jalila El Malki, Adil Maleb, Rachid Seddik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of International Medical Research, Vol 50 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1473-2300 03000605 |
| DOI: | 10.1177/03000605221109381 |
| Popis: | Objective Coronavirus disease 2019 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus 2. The clinical manifestations and the evolution of patients with COVID-19 are variable. In addition to respiratory involvement, COVID-19 leads to systemic involvement and can affect the hematopoietic system. This study aimed to evaluate the prognostic value of hematological and hemocytometric parameters in predicting the severity of patients with COVID-19. Methods We performed a retrospective study at Mohammed VI university Hospital from 1 March to 11 November 2020. We collected demographic characteristics and hematological findings of incident COVID-19 cases. Results A total of 245 patients were included in our study. We found that the rate of lymphopenia was significantly reduced in patients who were severely affected by COVID-19. Additionally, the rate of neutrophilia, the neutrophil side fluorescence light signal, monocyte fluorescent intensity, monocyte size, the neutrophil-to-lymphocyte ratio, the platelet-to-lymphocyte ratio, and the lymphocyte-to-monocyte ratio were significantly elevated in patients who were severely affected by COVID-19. Conclusions These results are consistent with the literature regarding the predictive value of these markers. A prospective validation in a large population with a longer follow-up is required. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|