Aurora A and Mcl-1: new potential treatment targets in antiestrogen-resistant breast cancer

Autor: Christina W. Yde
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Molecular & Cellular Oncology, Vol 8, Iss 6 (2021)
Druh dokumentu: article
ISSN: 2372-3556
23723556
DOI: 10.1080/23723556.2014.998898
Popis: Antiestrogen resistance is a major clinical limitation in treatment of breast cancer. We have recently reported that Aurora A and Mcl-1 (myeloid cell leukemia 1) are potential novel treatment targets in antiestrogen-resistant breast cancer cells and that Aurora A expression is a biomarker for tamoxifen resistance in breast cancer patients. Abbreviations: Bcl-2, B-cell lymphoma 2; EGF, epidermal growth factor; ERα, estrogen receptor α; Mcl-1, myeloid cell leukemia 1; VEGF, vascular endothelial growth factor.
Databáze: Directory of Open Access Journals
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