| Autor: |
Katherine A. Collins, Fabrisia Ambrosio, Renee J. Rogers, Wei Lang, Eric B. Schelbert, Kelliann K. Davis, John M. Jakicic |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Aging, Vol 4 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2673-6217 |
| DOI: |
10.3389/fragi.2023.1213228 |
| Popis: |
Introduction: Klotho is a protein associated with protection from aging-related diseases and health conditions. Obesity is associated with lower Klotho concentrations. Thus, this secondary analysis of adults with obesity examined 1) the change in serum Klotho concentration in response to a behavioral weight loss intervention by the magnitude of weight loss achieved; and 2) the association among serum Klotho concentration and weight, body composition, and cardiorespiratory fitness.Methods: Participants were randomized to either diet alone (DIET), diet plus 150 min of physical activity per week (DIET + PA150), or diet plus 250 min of physical activity per week (DIET + PA250). Participants [n = 152; age: 45.0 ± 7.9 years; body mass index (BMI): 32.4 ± 3.8 kg/m2] included in this secondary analysis provided blood samples at baseline, 6-, and 12 months, and were classified by weight loss response (Responder: achieved ≥10% weight loss at 6 or 12 months; Non-responder: achieved |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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