Patient Blood Management in Liver Transplant—A Concise Review

Autor: Angel Augusto Pérez-Calatayud, Axel Hofmann, Antonio Pérez-Ferrer, Carla Escorza-Molina, Bettina Torres-Pérez, Jed Raful Zaccarias-Ezzat, Aczel Sanchez-Cedillo, Victor Manuel Paez-Zayas, Raul Carrillo-Esper, Klaus Görlinger
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biomedicines, Vol 11, Iss 4, p 1093 (2023)
Druh dokumentu: article
ISSN: 2227-9059
DOI: 10.3390/biomedicines11041093
Popis: Transfusion of blood products in orthotopic liver transplantation (OLT) significantly increases post-transplant morbidity and mortality and is associated with reduced graft survival. Based on these results, an active effort to prevent and minimize blood transfusion is required. Patient blood management is a revolutionary approach defined as a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient’s own blood while promoting patient safety and empowerment. This approach is based on three pillars of treatment: (1) detecting and correcting anemia and thrombocytopenia, (2) minimizing iatrogenic blood loss, detecting, and correcting coagulopathy, and (3) harnessing and increasing anemia tolerance. This review emphasizes the importance of the three-pillar nine-field matrix of patient blood management to improve patient outcomes in liver transplant recipients.
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