Association between hyperacuity defects and retinal microstructure in polypoidal choroidal vasculopathy
| Autor: | Moosang Kim, Seung-Young Yu, Hyung-Woo Kwak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Color Doppler imaging
hypertensive retinopathy resistive index Conjunctival graft primary pterygium recurrent pterygium Intraocular pressure singleton pregnancy the number of fetuses twin pregnancy Accommodation agreement amplitude of accommodation push-up method Intraocular lens non-sclera flap transscleral pars plana suture fixation Axial length formulas lens power short eyes Acquired esotropia favourable outcome stereopsis Diabetic retinopathy enzyme-linked immunosorbent assay immunology interleukin-1β interleukin-10 proliferative Polypoidal choroidal vasculopathy preferential hyperacuity perimetry spectral-domain optical coherence tomography Ophthalmology RE1-994 |
| Zdroj: | Indian Journal of Ophthalmology, Vol 62, Iss 6, Pp 702-706 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| DOI: | 10.4103/0301-4738.121132 |
| Popis: | Purpose: To improve our understanding of hyperacuity defects measured with preferential hyperacuity perimetry (PHP) by correlating PHP findings with the retinal microstructural changes visible on spectral-domain optical coherence tomography (OCT) in patients with polypoidal choroidal vasculopathy (PCV). Materials and Methods: Twenty-eight eyes of 28 patients with PCV were retrospectively reviewed. All patients underwent a complete ophthalmologic examination, including best-corrected visual acuity (logMAR) testing, PHP, and OCT. The functional ′PHP test score′ and ′total volume of hyperacuity defect zone′ were also analyzed. Results: Patients were classified based on the hyperacuity defect by PHP, as follows: Hyperacuity defect (n = 17 eyes) group and hyperacuity intact (n = 11 eyes) group. The mean best-corrected visual acuity in the hyperacuity intact group (0.46 ± 0.39) was better than that in the hyperacuity defect group (0.82 ± 0.37) (P = 0.014). The presence of serous retinal detachment and retinal pigment epithelial detachment did not differ significantly between groups (P = 0.120 and P = 0.689, respectively). A disrupted photoreceptor layer was more common in the hyperacuity defect group compared with the hyperacuity intact group (P = 0.0001). Among 17 eyes with a hyperacuity defect, 9 eyes showing intra-retinal pathology (intra-retinal cyst or hard exudates) and had a significantly higher PHP test score and larger total volume of the hyperacuity defect zone than 8 eyes without intra-retinal pathology (P = 0.006 and P = 0.021, respectively). Conclusion: A hyperacuity defect in PCV was associated with photoreceptor disarrangement. Furthermore, PCV lesions on the inner retina that invaded the photoreceptor layer were associated with a more severe hyperacuity defect. |
| Databáze: | Directory of Open Access Journals |
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