Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis

Autor:	Shih-Jie Lo, Da-Jeng Yao
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	microfluidic techniques single-cell manipulation single-cell analysis Biology (General) QH301-705.5 Chemistry QD1-999
Zdroj:	International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 16763-16777 (2015)
Druh dokumentu:	article
ISSN:	1422-0067 16081676
DOI:	10.3390/ijms160816763
Popis:	This review describes the microfluidic techniques developed for the analysis of a single cell. The characteristics of microfluidic (e.g., little sample amount required, high-throughput performance) make this tool suitable to answer and to solve biological questions of interest about a single cell. This review aims to introduce microfluidic related techniques for the isolation, trapping and manipulation of a single cell. The major approaches for detection in single-cell analysis are introduced; the applications of single-cell analysis are then summarized. The review concludes with discussions of the future directions and opportunities of microfluidic systems applied in analysis of a single cell.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e7ff59b27bb3472b9f990957218b749e Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF