| Autor: |
Jaffar A. Al-Tawfiq, Mahmoud Abed, Bassam M. Saadeh, Jihad Ghandour, Mohammad Shaltaf, Mohamed M. Babiker |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Journal of Infection and Public Health, Vol 4, Iss 5, Pp 228-234 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
1876-0341 |
| DOI: |
10.1016/j.jiph.2011.09.005 |
| Popis: |
Summary: Background and objectives: The World Health Organization (WHO) declared that pandemic influenza A (H1N1) was a public health emergency of international concern in April 2009. Herein, we describe the characteristics of patients in a Saudi Arabian hospital with and without H1N1 infection. Methods: We reviewed the records of patients admitted with influenza-like illness and compared confirmed pandemic H1N1 cases to the H1N1-negative patients admitted to the hospital. Infections due to the novel H1N1 virus were confirmed using real-time reverse transcriptase polymerase chain reaction (rRT-PCR). Results: During the study period, a total of 165 patients were admitted with influenza-like illness and underwent rRT-PCR testing. Of these patients, 47 (28.4%) had confirmed novel H1N1 virus infection. Thus, the hospitalization incidence rate was 13.4 cases per 100,000 persons. The remaining patients had negative H1N1 rRT-PCR test results. The mean age ± SD of the H1N1-positive patients was 30.3 ± 28.5 years compared with 25.3 ± 23 years for the H1N1-negative group (P = 0.28). Severe obesity was observed in 6.7% and 8.5% of H1N1-positive and H1N1-negative patients, respectively (P = 0.74). The clinical picture was similar between the two groups, except for the higher prevalence of nausea (25.5% vs. 11%) and diarrhea (21.3% vs. 7.6%) in the H1N1-positive group than in the H1N1-negative group (P = 0.03) The mortality rate was low in both groups. Conclusion: The clinical presentation and outcome are insufficient to differentiate between influenza-like illness (ILI) caused by H1N1 and that cause by other pathogens. In general, both groups had mild disease in this cohort of patients in Saudi Arabia. Keywords: Influenza, Vaccination, H1N1, Pandemic |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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