In Situ Deposition of Drug and Gene Nanoparticles on a Patterned Supramolecular Hydrogel to Construct a Directionally Osteochondral Plug

Autor:	Jiawei Kang, Yaping Li, Yating Qin, Zhongming Huang, Yifan Wu, Long Sun, Cong Wang, Wei Wang, Gang Feng, Yiying Qi
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Osteochondral regeneration Oriented hydrogel Kartogenin miRNA-26a Technology
Zdroj:	Nano-Micro Letters, Vol 16, Iss 1, Pp 1-19 (2023)
Druh dokumentu:	article
ISSN:	2311-6706 2150-5551
DOI:	10.1007/s40820-023-01228-w
Popis:	Highlights A multifactorial and oriented scaffolds was constructed to stimulate osteochondral regeneration. This is the first demonstration that both drug and gene nanoparticles were spatially deposited on a patterned film through metal-ligand interactions. For the first time, film-rolling approach was employed to construct osteochondral plug to mimick the Haversian canal structure of natural bone.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7fdaa2fc00884a4885b73e022608afe3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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