The acute influence of vasopressin on hemodynamic status and tissue oxygenation following the Norwood procedureCentral MessagePerspective

Autor: Ronald A. Bronicki, MD, Sebastian Acosta, PhD, Fabio Savorgnan, MD, Saul Flores, MD, Barbara-Jo Achuff, MD, Rohit Loomba, MD, Mubbasheer Ahmed, MD, Nancy Ghanayem, MD, MS, Jeffrey S. Heinle, MD, Vicken Asadourian, BS, Javier J. Lasa, MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JTCVS Open, Vol 9, Iss , Pp 217-224 (2022)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2022.01.008
Popis: Objectives: Arginine vasopressin (AVP) is used to treat hypotension. Because AVP increases blood pressure by increasing systemic vascular resistance, it may have an adverse effect on tissue oxygenation following the Norwood procedure. Methods: Retrospective analysis of continuously captured hemodynamic data of neonates receiving AVP following the Norwood procedure. Results: We studied 64 neonates exposed to AVP within 7 days after the Norwood procedure. For the entire group, AVP significantly increased mean blood pressure (2.5 ± 6.3) and cerebral and renal oxygen extraction ratios (4.1% ± 9.6% and 2.0% ± 4.7%, respectively; P
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