Nutritional factors associated with mortality in hospitalized patients with COVID-19

Autor: Clíslian Luzia da Silva, Thaís Muniz Montalvão Sousa, Josimar Barbosa de Sousa Junior, Eduardo Yoshio Nakano
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Clinical Nutrition Open Science, Vol 45, Iss , Pp 17-26 (2022)
Druh dokumentu: article
ISSN: 2667-2685
DOI: 10.1016/j.nutos.2022.08.001
Popis: Summary: Background & aims: Malnutrition is a risk factor that can lead to diminished physical and mental function and impaired clinical outcome from diseases. This study was performed to investigate the influence of nutritional characteristics, age and the presence of pre-comorbidities in hospital mortality or medical discharge in a sample of hospitalized patients with COVID-19. Methods: This historical cohort study was conducted in adults and elderly patients with COVID-19 who were admitted to a nursing ward at the University Hospital of Brasilia (Brazil). Data regarding demographics, comorbidities, laboratory parameters, nutritional characteristics (NRS 2002, SARC-F, BMI) and discharge or death were retrospectively extracted from medical records. Differences in each group (in-hospital mortality or discharge) were assessed using unpaired Student's t test for continuous variables, or Pearson Chi-square tests for categorical data. Results: A total of 222 patients with COVID-19 were enrolled in this study. Nutritional risk and sarcopenia risk were higher in patients who died compared to patients who were discharged (3.55 ± 1.30 vs 2.96 ± 1.30; p = 0.005, 6.81 ± 1.84 vs 4.96 ± 2.95; p
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