Renal Functions in Relation to Severity of Perinatal Asphyxia in Term Neonates
| Autor: | Dinesh Kumar, Mukesh Vir Singh, Niraj Kumar, Durgesh Kumar, Krishan Mohan Shukla, Kalbe Jawad |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Indian Journal of Neonatal Medicine and Research, Vol 8, Iss 3, Pp 07-11 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2277-8527 2455-6890 |
| DOI: | 10.7860/IJNMR/2020/44591.2271 |
| Popis: | Introduction: Kidney is one of the most important organs commonly involved in the multiple organ dysfunction caused by perinatal asphyxia. Monitoring the serum urea, creatinine and urine output helps in early assessment of severity of perinatal asphyxia and, thus improving the outcome. Aim: To study renal functions in perinatal asphyxia and various stages of Hypoxic-Ischemic Encephalopathy (HIE) in term neonates. Materials and Methods: This observational study included 118 full-term perinatally asphyxiated neonates admitted in Neonatal Intensive Care Unit (NICU) of Uttar Pradesh University of Medical Sciences, Saifai, Etawah. Serum urea, creatinine and urine output were assessed on 1st, 3rd and 10th day of admission. A total of 48 newborns with normal Renal Function Test (RFT) and urine output were kept in Group A, while 70 newborn with abnormal RFT and urine output were kept in Group B. To compare RFT in various HIE stages of perinatal asphyxia, neonates were graded by the Levene staging system and divided in mild HIE (stage I), moderate HIE (stage II) and severe HIE (stage III). A total of 52 neonates who did not fulfill criteria of any stage of Levene were diagnosed as asphyxia without HIE and were excluded from comparison. Results: Significant differences (p-value |
| Databáze: | Directory of Open Access Journals |
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