| Autor: |
Seref Kerem Corbacıoglu, MD, Yunsur Cevik, MD, Emine Akinci, MD, Hüseyin Uzunosmanoglu, MD, Seda Dagar, MD, Tuba Safak, MD, Veysel Oncul, Murat Guvendi |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Turkish Journal of Emergency Medicine, Vol 17, Iss 3, Pp 85-88 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2452-2473 |
| DOI: |
10.1016/j.tjem.2017.03.002 |
| Popis: |
Objective: In this study, we aimed to determine whether plasma NGAL levels could be used as a biomarker for distinguishing between AKI and CKD in emergency medicine. Materials and methods: This prospective study was conducted at the ED of a training and research hospital over a six-month period in 2015. Three groups were defined: an AKI group – defined as a new onset of at least a 1.5-fold or ≥0.3 mg increment increase of SCr values from the normal baseline, a stable CKD group – only included presence of stages 2 through 4 of CKD according to the National Kidney Foundation's KDIGO 2012, and a control group. After the initial evaluation of patients, venous blood samples were taken for routine biochemical, counter blood cell, and plasma NGAL measurement at admission. Results: A total of 25 patients with AKI, 22 patients with stable CKD, and 22 control subjects were enrolled. Level of plasma NGAL in AKI group was higher than those of the stable CKD group (median: 794 ng/ml IQR: 317–1300 & 390 ng/ml IQR: 219–664, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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