Autor: |
Holis Abdul Holik, Faisal Maulana Ibrahim, Angela Alysia Elaine, Bernap Dwi Putra, Arifudin Achmad, Achmad Hussein Sundawa Kartamihardja |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Molecules, Vol 27, Iss 10, p 3062 (2022) |
Druh dokumentu: |
article |
ISSN: |
1420-3049 |
DOI: |
10.3390/molecules27103062 |
Popis: |
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as a result of the growing research interest in personalized medicine to improve diagnostic accuracy and intensify intensive therapy while limiting side effects. Radiometal-based drugs are of substantial interest because of their greater versatility for clinical translation compared to non-metal radionuclides. This paper comprehensively discusses various components commonly used as chemical scaffolds to build radiopharmaceutical agents, i.e., radionuclides, pharmacokinetic-modifying linkers, and chelators, whose characteristics are explained and can be used as a guide for the researcher. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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