Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease

Autor: Eli Magen, Viktor Feldman, Mishal Joseph, Hadari Israel
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Case Reports in Immunology, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 2090-6609
2090-6617
DOI: 10.1155/2012/684247
Popis: Selective IgM immunodeficiency (SIgMID) is a heterogeneous disorder with no known genetic background and may occur as a primary or a secondary condition. Celiac disease has been reported in association with several humeral immunodeficiencies, including isolated severe selective IgA deficiency, panhypogammaglobulinemia, and isolated combined IgA and IgM deficiency. There are only few reported cases of pediatric and adult patients with SIgMID and celiac disease. In this paper, we describe an adult patient with a symptomatic secondary SIgMID associated with undiagnosed celiac disease, with a resolution of clinical symptoms of immunodeficiency and serum IgM normalization following a gluten-free diet.
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