Background incidence rates of health outcomes of interest for COVID-19 vaccine safety monitoring in a US population: a claims database analysis

Autor: Sonja Banga, Alena Khromava, Laurence Serradell, Anne-Laure Chabanon, Chunshen Pan, Irisdaly Estevez, Samantha Schilsky, Hannah Kreisberg
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Open, Vol 14, Iss 7 (2024)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2024-083947
Popis: Objective To evaluate background incidence rates of 59 health outcomes of interest (HOI) in a diverse population, including important subpopulations, during the pre-COVID-19 era (1 January 2017–31 December 2019) and the COVID-19 era (1 March 2020–31 December 2020), before the introduction of COVID-19 vaccines.Design Observational retrospective cohort study. Annual incidence rates and 95% confidence intervals (CIs) of HOIs were estimated for each population of interest, stratified by: age, sex, age and sex and seasonality.Data source Optum’s de-identified Clinformatics Data Mart Database (CDM).Participants Individuals from the US general population and four subgroups of interest: influenza-vaccinated, paediatric (
Databáze: Directory of Open Access Journals