Efficacy and safety of CSA withdrawal in children late after kidney transplantation

Autor: Mikhail Mikhaylovich Kaabak, Nadezhda Nikolaevna Babenko, Elena Aleksandrovna Molchanova, Alan Kimovich Zokoev, Zhanna Ivanovna Kurakina, Viktor Andreevich Goryaynov, Marina Gennadievna Minina, Ravil' Borisovich Akhmetshin, M M Kaabak, N N Babenko, E A Molchanova, A K Zokoev, L Kurakina, V A Goryainov, M G Minina, R B Akhmetshin
Jazyk: ruština
Rok vydání: 2009
Předmět:
Zdroj: Терапевтический архив, Vol 81, Iss 8, Pp 62-64 (2009)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: Aim. Evaluation of cyclosporine (CSA) withdrawal safety and efficacy in children late after kidney transplantation. Material and methods. Graft and patient survival was analysed in 30 kidney recipients operated in the central children's hospital in 1991-1999. Fifteen of 30 patients came for follow-up to the Russian Research Center for Surgery where CsA was withdrawn 6.8 ± 2.7 after transplantation. The other 15 children continued immunosuppression with CsA. Results. Higher graft survival was observed in children in whom CsA was discontinued. Conclusion. Discontinuation of cyclosporine late after kidney transplantation results in improvement of graft survival in most of the patients.
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