| Autor: |
Myriam M. Ouberai, Ana L. Gomes Dos Santos, Sonja Kinna, Shimona Madalli, David C. Hornigold, David Baker, Jacqueline Naylor, Laura Sheldrake, Dominic J. Corkill, John Hood, Paolo Vicini, Shahid Uddin, Steven Bishop, Paul G. Varley, Mark E. Welland |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-01114-1 |
| Popis: |
The clinical potential of peptide therapeutic agents can only be fully realised once their physicochemical and pharmacokinetic properties are precisely controlled. Here the authors show a reversible peptide self-assembly strategy to control and prolong the bioactivity of a native peptide hormone in vivo. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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