High level of DNA

Autor: Fadi B. Choucair, Eliane G. Rachkidi, Georges C. Raad, Elias M. Saliba, Nina S. Zeidan, Rania A. Jounblat, Imad F. Abou Jaoude, Mira M. Hazzouri
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Middle East Fertility Society Journal, Vol 21, Iss 4, Pp 269-276 (2016)
Druh dokumentu: article
ISSN: 1110-5690
DOI: 10.1016/j.mefs.2016.06.005
Popis: Assessment of male fertility has been based on routine semen analysis established by the World Health Organization (WHO), evaluating sperm concentration, motility and morphology. Actually, these parameters become less reliable markers to evaluate male fertility potential. Therefore, a search for better markers has led to an increased focus on sperm chromatin integrity testing in fertility work-up and assisted reproductive technologies (ART). In this study, we evaluate sperm DNA fragmentation in 185 Lebanese infertile patients attending fertility clinics all over the country, in comparison with 30 control men of proven fertility, using the sperm chromatin dispersion test (SCD). Our results showed a significantly higher sperm DNA fragmentation in infertile group compared to control group (20.62% vs 12.96%; p
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