Primary malignancy in giant cell tumor: a case report

Autor: Rosalvo Zósimo Bispo Júnior, Olavo Pires de Camargo, Cristiane Marie Ida, André Mathias Baptista, Marcelo Barbosa Ribeiro, José Marcello Bruno, Cláudia Regina Gomes Cardim Mendes de Oliveira
Jazyk: angličtina
Předmět:
Zdroj: São Paulo Medical Journal, Vol 127, Iss 5, Pp 310-313
Druh dokumentu: article
ISSN: 1806-9460
1516-3180
DOI: 10.1590/S1516-31802009000500011
Popis: CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does. CASE REPORT: This report presents the case of a 39-year-old female with pain in her left shoulder for one month. Radiography showed a pathological fracture of the proximal humerus associated with an osteolytic lesion. Histopathological analysis showed typical areas of GCT juxtaposed with a sarcomatous component. CONCLUSIONS: PMGCT seems to behave less aggressively than secondary malignancy in GCT, and it may simulate its more common benign counterpart clinically and radiographically. However, it requires a more aggressive type of treatment.
Databáze: Directory of Open Access Journals