Autor: |
Rouhina Movaghar, Shamci Abbasalizadeh, Shabnam Vazifekhah, Azizeh Farshbaf-Khalili, Mahnaz Shahnazi |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Women's Health, Vol 24, Iss 1, Pp 1-12 (2024) |
Druh dokumentu: |
article |
ISSN: |
1472-6874 |
DOI: |
10.1186/s12905-024-02922-6 |
Popis: |
Abstract Introduction Preeclampsia affects a significant percentage of pregnancies which is a leading cause of premature birth. Probiotics have the potential to affect inflammatory factors, and oxidative stress, which are linked to the development of preeclampsia. The study aimed to compare the effect of synbiotic and placebo on blood pressure and pregnancy duration as primary outcomes, and other pregnancy outcomes. Methods This study comprised 128 pregnant women with mild preeclampsia and gestational ages exceeding 24 weeks who were referred to the high-risk pregnancy clinic. It was a randomized, controlled, phase III, triple-blinded clinical experiment. The intervention and control groups were distributed to the participants at random. Intervention group received one oral synbiotic capsule, and control group received placebo daily until delivery. Based on gestational age at the time of diagnosis, preeclampsia was stratificated as early ( |
Databáze: |
Directory of Open Access Journals |
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