Small Heat Shock Proteins in Retinal Diseases

Autor: Vivian Rajeswaren, Jeffrey O. Wong, Dana Yabroudi, Rooban B. Nahomi, Johanna Rankenberg, Mi-Hyun Nam, Ram H. Nagaraj
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Molecular Biosciences, Vol 9 (2022)
Druh dokumentu: article
ISSN: 2296-889X
DOI: 10.3389/fmolb.2022.860375
Popis: This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.
Databáze: Directory of Open Access Journals