Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma

Autor:	L. V. Bolotina, T. V. Ustinova, T. I. Dеshkina, P. V. Golubev, N. N. Lyubavina, A. A. Fedenko, A. D. Kaprin
Jazyk:	ruština
Rok vydání:	2022
Předmět:	head and neck tumors chemotherapy monoclonal antibodies cetuximab immunotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Опухоли головы и шеи, Vol 12, Iss 1, Pp 35-52 (2022)
Druh dokumentu:	article
ISSN:	2222-1468 2411-4634
DOI:	10.17650/2222-1468-2022-12-1-35-52
Popis:	This article discusses current approaches to first-line chemotherapy for non-resectable head and neck squamous cell carcinoma and describes factors affecting the choice of treatment regimen according to the results of randomized clinical trials. We provide a rationale for creating a long-term strategy of chemotherapy in different clinical situations. We also report two cases of concomitant administration of cetuximab and platinum-based therapy as an example of high efficacy of monoclonal antibodies.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7ef5a787f1684a399160ab6d43dca91e Zobrazit plný text záznamu View record in DOAJ