In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

Autor: Oleksandr Oleshko, Iryna Liubchak, Yevheniia Husak, Viktoriia Korniienko, Aziza Yusupova, Tetiana Oleshko, Rafal Banasiuk, Marek Szkodo, Igor Matros-Taranets, Alicja Kazek-Kęsik, Wojciech Simka, Maksym Pogorielov
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Materials, Vol 13, Iss 19, p 4359 (2020)
Druh dokumentu: article
ISSN: 1996-1944
DOI: 10.3390/ma13194359
Popis: Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium–phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.
Databáze: Directory of Open Access Journals
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