CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion

Autor: Enrico S. Atorino, Shoji Hata, Charlotta Funaya, Annett Neuner, Elmar Schiebel
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-14767-2
Popis: During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear. Here, the authors report that the centriole microtubule-triplet 9-fold structure scaffolds pericentriolar proteins and permits the conversion of centrioles to fully functional centrosomes.
Databáze: Directory of Open Access Journals