Monkeypox Virus Evolution before 2022 Outbreak

Autor:	Eric Dumonteil, Claudia Herrera, Gilberto Sabino-Santos
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Monkeypox virus MPXV mpox transmission evolution adaptation Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 29, Iss 2, Pp 451-453 (2023)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2902.220962
Popis:	Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a7ec86e189f245168be7bf9da8efe4dc Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF