| Autor: |
Charles H. Duncan, Maurice M. Best |
| Jazyk: |
angličtina |
| Rok vydání: |
1960 |
| Předmět: |
|
| Zdroj: |
Journal of Lipid Research, Vol 1, Iss 2, Pp 159-163 (1960) |
| Druh dokumentu: |
article |
| ISSN: |
0022-2275 |
| DOI: |
10.1016/S0022-2275(20)39077-5 |
| Popis: |
The effect of the addition of 1 per cent nicotinic acid to the diet of the rat on serum, liver, and carcass cholesterol, and on the incorporation of acetate-1-C14 into cholesterol by the intact animal were studied. The effect of nicotinic acid on absorption of cholesterol-4-C14 and on the elimination of labeled cholesterol from serum and liver were also studied. No significant effect of nicotinic acid, fed for either 8 or 42 days, on the incorporation of acetate-l-C14 into serum and liver cholesterol was observed. When weight gain of the control animals was limited to that of the nicotinic-acid-fed rats by pair-feeding, nicotinic acid had no significant effect on serum or liver cholesterol concentrations, nor on total carcass cholesterol. Absorption of cholesterol-4-C14 and the disappearance of labeled cholesterol from serum and liver were not influenced by nicotinic acid administration by stomach tube. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
