Plasma B-type Natriuretic Peptide Level in Patients with Acute Cerebral Infarction according to Infarction Subtype and Infarction Volume

Autor: Seo Hyun Kim, Ji-Yong Lee, Sang Hyun Park, Hyun-Chan Jang, Eun Ju Lim, Sei-Jin Chang, Sung-Soo Lee
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Medical Sciences, Vol 10, Iss 1, Pp 103-109 (2013)
Druh dokumentu: article
ISSN: 1449-1907
Popis: Background: Plasma B-type natriuretic peptide (BNP) is used as a diagnostic marker of cardiovascular diseases. BNP is secreted mainly from the myocardium and has been detected by immunoreactivity in brain and cerebral arteries. The aim of our study was to investigate plasma BNP in patients with acute cerebral infarction according to infarction subtype and infarction volume.Methods: We studied 141 patients with acute cerebral infarction, classified as large artery atherosclerosis (LAA), cardioembolism (CE), or small vessel disease (SA) according to the Trial of Org 10172 in Acute Stroke Treatment classification. Plasma BNP level was measured in patients and 61 healthy controls. We analyzed various clinical and laboratory variables of patients according to plasma BNP level.Results: Compared to controls, the patients had higher plasma BNP (11.9 ± 11.7 pg/mL versus 124.6 ± 228.8 pg/mL, p Conclusions: Plasma BNP may be helpful for prediction of etiologic classification of acute cerebral infarction and infarction volume.
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