Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan

Autor: Abdelhafid Karrat, Aziz Amine
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chemosensors, Vol 10, Iss 11, p 450 (2022)
Druh dokumentu: article
ISSN: 2227-9040
DOI: 10.3390/chemosensors10110450
Popis: Bisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazole (Chitosan-PAD) for the visual detection of BPA in water. The PAD was characterized by Fourier-transform infrared spectroscopy, which confirmed its modification by the functionalized chitosan. A yellow coloration was developed when a small volume of BPA was added to the Chitosan-PAD, allowing for visual and smartphone detection. This new strategy is based on a specific combination of BPA with chitosan and sulfamethoxazole that provides a hight selectivity to the Chitosan-PAD. The proposed PAD was successfully employed in combination with a pre-concentration step for the detection of 0.01 µg mL−1 of PBA with the naked eye using a 10-fold preconcentration factor. The PAD was effectively applied for BPA quantification in water samples with good recoveries. The developed PAD provides a green and cost-effective strategy for the on-site and one-step detection of BPA in water samples.
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