Cell specific peripheral immune responses predict survival in critical COVID-19 patients

Autor: Junedh M. Amrute, Alexandra M. Perry, Gautam Anand, Carlos Cruchaga, Karl G. Hock, Christopher W. Farnsworth, Gwendalyn J. Randolph, Kory J. Lavine, Ashley L. Steed
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28505-3
Popis: Infection with SARS-CoV-2 results in activation of multiple immune cell types in situ but also in the peripheral blood compartment. Here the authors apply single cell sequencing and machine learning to characterise the response and link this to confer prognostic indicators in critically ill COVID-19 patients.
Databáze: Directory of Open Access Journals