Real-world use of ticagrelor versus clopidogrel in percutaneous coronary intervention-treated ST-elevation myocardial infarction patients: A single-center registry study

Autor: Leia Hee, Oliver J. Gibbs, Joseph G. Assad, Lokesh D. Sharma, Andrew Hopkins, Craig P. Juergens, Sidney Lo, Christian J. Mussap
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the Saudi Heart Association, Vol 31, Iss 4, Pp 151-160 (2019)
Druh dokumentu: article
ISSN: 1016-7315
DOI: 10.1016/j.jsha.2019.05.005
Popis: Objectives: The primary aim was to investigate the efficacy and safety of dual antiplatelet therapy (DAPT) using ticagrelor (T-DAPT) versus clopidogrel (C-DAPT) in a real-world ST-elevation myocardial infarction (STEMI) population. Methods: We retrospectively analyzed 655 consecutive patients having primary percutaneous coronary intervention (PCI) for STEMI at Liverpool Hospital, Sydney, Australia (from January 2013 to April 2016). Medical and procedural therapies were at clinician discretion. Patient data were retrieved from hospital records and primary clinicians. Results: T-DAPT (65%) was used more frequently, and in patients with lower mean CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association Guidelines) score, than C-DAPT (24.6 vs. 32.2; p
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