| Autor: |
SANDRA S. KONSTANTINOVIC, BLAGA C. RADOVANOVIC, SOFIJA P. SOVILJ, SVETLANA STANOJEVIC |
| Jazyk: |
angličtina |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Journal of the Serbian Chemical Society, Vol 73, Iss 1, Pp 7-13 (2008) |
| Druh dokumentu: |
article |
| ISSN: |
0352-5139 |
| Popis: |
Isatin-3-thiosemicarbazone complexes with Co(II), Ni(II), Cu(II), Zn(II), Hg(II) and Pd(II) were synthesized and evaluated for their antimicrobial activity against 7 pathogenic bacteria and 4 fungi. The complexes have an enhanced activity compared to the ligand due to transition metal involved in coordination. The anti-amoebic activity in vitro was evaluated against the HM1:IMSS strain of Entamoeba histolytica and the results were compared with the standard drug, metronidazole. The preliminary test results showed that the complexes had better anti-amoebic activity than their respective ligands. Moreover, the complexes showed better inhibition of the test organism. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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