Single shot of 17D vaccine may not confer life-long protection against yellow fever

Autor: Pedro FC Vasconcelos
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 2, Pp 135-137 (2017)
Druh dokumentu: article
ISSN: 1678-8060
0074-0276
DOI: 10.1590/0074-02760170347
Popis: The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus . Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.
Databáze: Directory of Open Access Journals