Influence of pharmacogenetics on the diversity of response to statins associated with adverse drug reactions

Autor: Sainz de Medrano Sainz Jaime I., Brunet Serra Mercè
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2023
Předmět:
Zdroj: Advances in Laboratory Medicine, Vol 4, Iss 4, Pp 341-352 (2023)
Druh dokumentu: article
ISSN: 2628-491X
DOI: 10.1515/almed-2023-0123
Popis: Statins are one of the most prescribed medications in developed countries as the treatment of choice for reducing cholesterol and preventing cardiovascular diseases. However, a large proportion of patients experience adverse drug reactions, especially myotoxicity. Among the factors that influence the diversity of response, pharmacogenetics emerges as a relevant factor of influence in inter-individual differences in response to statins and can be useful in the prevention of adverse drug effects.
Databáze: Directory of Open Access Journals