ANTI-INFLAMMATORY EFFECT OF Myrtus nivellei Batt & Trab (MYRTACEAE) METHANOLIC EXTRACT

Autor: M. Touaibia, F. Z. Chaouch
Jazyk: English<br />French
Rok vydání: 2015
Předmět:
Zdroj: Journal of Fundamental and Applied Sciences, Vol 7, Iss 1, Pp 77-82 (2015)
Druh dokumentu: article
ISSN: 1112-9867
DOI: 10.4314/fas.v7i1.6
Popis: This work aims at evaluating the anti-inflammatory activity of an endemic species of the central sahara: Myrtus nivellei Batt & Trab. The methanolic extract of this plant was extracted by Soxhlet apparatus and concentrated under reduced pressure using a rotary evaporator. In the carrageenan-induced paw edema test, five different groups of mice were established and the extract was administered orally in three different doses. The dose of 400 mg/kg was able to reduce significantly the paw edema with a comparable effect to that observed with Diclofenac (positive control). This is the first report to demonstrate a significant anti-inflammatory activity of the methanolic extract prepared from Myrtus nivellei.
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