Study of clinical and histopathological factors predicting rapid progression in biopsy-proven type 2 diabetic kidney disease
| Autor: | Shilna Muttickal Swaminathan, Mohan Varadanayakanahalli Bhojaraja, Ravindra Prabhu Attur, Indu Ramachandra Rao, Dharshan Rangaswamy, Srinivas Vinayak Shenoy, Shankar Prasad Nagaraju |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Nephropathology, Vol 13, Iss 4, Pp e21516-e21516 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2251-8363 2251-8819 |
| DOI: | 10.34172/jnp.2023.21516 |
| Popis: | Introduction: Rapid progression of diabetic kidney disease (DKD) is a significant concern, particularly in developing countries. It remains uncertain whether histopathological parameters, in addition to clinical factors, can predict DKD progression. Objectives: To evaluate renal histopathological and clinical parameters in predicting rapid progression to end-stage kidney disease (ESKD) in type 2 diabetes mellitus (Type 2 DM) patients with biopsy-proven DKD. Patients and Methods: This was an observational retrospective study that included 49 biopsy-proven DKD from January 2018 to December 2022. Those with less than six months of follow-up and CKD stage 5 were excluded. The outcomes studied were rapid progression and progression to ESKD. Patients were categorized into rapid progressors and non-progressors based on the estimated glomerular filtration (eGFR) decline of > or |
| Databáze: | Directory of Open Access Journals |
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