| Autor: |
Wei Yue, Nan Meng, Jing Wang, Wenling Liu, Xuejia Wang, Minghuan Yan, Dongming Han, Jingliang Cheng |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Cancer Imaging, Vol 19, Iss 1, Pp 1-9 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1470-7330 |
| DOI: |
10.1186/s40644-019-0196-6 |
| Popis: |
Abstract Purpose This study evaluated and compared the performances of diffusion kurtosis imaging (DKI) and diffusion-weighted imaging (DWI) for diagnosing and histologically grading endometrial cancer. Materials and methods In this retrospective study, DKI and DWI data for 61 patients with endometrial cancer and 30 patients with a normal endometrium were analyzed, and the mean kurtosis (MK), mean diffusion coefficient (MD) and apparent diffusion coefficient (ADC) values for the endometrial cancer tissue and normal endometrial tissue were acquired. The parameters for the normal endometrium group (G0) and the endometrial cancer groups (G1, G2 and G3) were compared and analyzed. The receiver operating characteristic (ROC) curve was used to evaluate each parameter’s diagnostic accuracy and threshold. Spearman correlation analysis was used to analyze the correlations between all parameters and histological grades. Results The MK values for the G0, G1, G2 and G3 groups increased gradually, while the MD and ADC values decreased gradually. Except for the differences in the ADC values between G0 and G1, the differences among the groups were statistically significant (P MD > ADC; r = − 0.85, + 0.82, + 0.76, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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