| Autor: |
Andressa R. Amaral, Márcio A. Brunetto, Marina P. Brólio, Daniela S. Cima, Maria A. Miglino, João Paulo F. Santos, Carlos E. Ambrósio |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Journal of Nutritional Science, Vol 6 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2048-6790 |
| DOI: |
10.1017/jns.2017.59 |
| Popis: |
The canine golden retriever muscular dystrophy (GRMD) model is the best animal model for studying Duchenne muscular dystrophy in humans. Considering the importance of glucose metabolism in the muscles, the existence of metabolic and endocrine alterations in a wide range of muscular dystrophies, and the pre-existing relationship between blood insulin concentration and muscular atrophy, the present study aimed to evaluate the postprandial glucose and insulin response in GRMD dogs. A total of eighteen golden retriever dogs were randomly distributed into three experimental groups: healthy/control (G1), female GRMD carriers (G2), and male dogs affected by GRMD (G3). Higher plasma resting glucose levels (P = 0·0047) were seen in G2 and G3 compared with G1, as was the case for minimum (P = |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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