Autor: |
Maria Angela Gomes de Castro, Hanna Wildhagen, Shama Sograte-Idrissi, Christoffer Hitzing, Mascha Binder, Martin Trepel, Niklas Engels, Felipe Opazo |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-019-08677-1 |
Popis: |
Signalling of the B cell receptor (BCR) is pivotal for survival and activation of naïve B cells. Here the authors show, using super-resolution microscopy techniques, that BCRs exist primarily as monomers and dimers in resting B cells, and oligomerize only on stimulation, thereby implicating a function of BCR clustering patterns on B cell biology. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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