| Autor: |
O.O. Dosumu, A.A.A. Osinubi, F.I.O. Duru |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Middle East Fertility Society Journal, Vol 19, Iss 3, Pp 221-228 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1110-5690 |
| DOI: |
10.1016/j.mefs.2014.01.003 |
| Popis: |
Drinking continues to be a major problem in many parts of the world. Significant effects on testicular morphology and function in animals as well as man have been well described. To further explore the impact of chronic ethanol exposure on the testes, we designed this study specifically to define whether or not there was complete recovery after abstinence by examining reproductive hormones, testicular histomorphometry, testicular antioxidants as well as semen parameters after ethanol exposure. Sexually mature male Sprague–Dawley rats were randomly divided into control, abstinent and non-abstinent groups. Alcohol was administered orally at 7 ml/kg body weight per day thrice in a week for 2, 4 and 8 weeks. Control animals received an equivalent amount of distilled water. Histological analysis of the seminiferous tubules of the animals in the non-abstinent group showed severe reduction of cells of the spermatogenic series, hypocellularity, tubular atrophy and significant reductions in the tubular diameter and cross-sectional areas (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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