Predicting developmental dysplasia of the hip in at-risk newborns

Autor: Andreas Roposch, Evangelia Protopapa, Olivia Malaga-Shaw, Yael Gelfer, Paul Humphries, Deborah Ridout, John H. Wedge
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Musculoskeletal Disorders, Vol 21, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 1471-2474
DOI: 10.1186/s12891-020-03454-4
Popis: Abstract Background The development of developmental dysplasia of the hip can be attributed to several risk factors and often in combination with each other. When predicting the likelihood of developing this condition, clinicians tend to over and underestimate its likelihood of occurring. Therefore, the study aim is to determine among at-risk newborns how to best predict developmental dysplasia of the hip (DDH) within 8 weeks post-partum. Methods Prospective cohort study in secondary care. Patient population included newborns at-risk for DDH – we assessed 13,276 consecutive newborns for the presence of DDH risk factors. Only newborns with at least one of the predefined risk factors and those showing an abnormal examination of the hip were enrolled (n = 2191). For the development of a risk prediction model we considered 9 candidate predictors and other variables readily available at childbirth. The main outcome measure was ultrasonography at a median age of 8 weeks using consensus diagnostic criteria; outcome assessors were blinded. Results The risk model includes four predictors: female sex (OR = 5.6; 95% CI: 2.9–10.9; P 4000 g (OR = 1.6; 95% CI: 0.6–4.2; P = 0.34), and abnormal examination of hip (OR = 58.8; 95% CI: 31.9, 108.5; P
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