Association of HLA class II alleles with suicidal behavior in a Transylvanian population

Autor: Vuscan Mihaela Elvira, Vica Mihaela Laura, Balici Stefana, Nicula Gheorghe Zsolt, Rusu Sergiu Ionica, Siserman Costel Vasile, Coman Horia George, Matei Horea Vladi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Romanian Journal of Laboratory Medicine, Vol 31, Iss 1, Pp 15-24 (2023)
Druh dokumentu: article
ISSN: 2284-5623
2023-0001
DOI: 10.2478/rrlm-2023-0001
Popis: Background: Suicide is a complex phenomenon determined by the interaction of various risk factors. The Major Histocompatibility Complex is the most polymorphic gene cluster of the entire human genome, being linked to both the regulation of the immune system and various psychiatric diseases. The aim of this study was to identify HLA-DQB1 and DRB1 alleles and genotypes susceptible to influence suicidal behavior.
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