Quantification of relative afferent pupillary defect by an automated pupillometer and its relationship with visual acuity and dimensions of macular lesions in age-related macular degeneration

Autor: Renu P Rajan, Amit K Deb, Sonali Lomte, Claudio M Privitera, Naresh B Kannan, Kim Ramasamy, Ravilla D Ravindran
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 69, Iss 10, Pp 2746-2750 (2021)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/ijo.IJO_3509_20
Popis: Purpose: The occurrence of relative afferent pupillary defect (RAPD) secondary to optic nerve diseases and widespread retinal disorders is well established. However, only very few reports of RAPD in macular disorders exist in the literature. In this study, we used automated pupillometer to evaluate RAPD in eyes with macular lesions. Methods: It was a prospective cross-sectional study. A total of 82 patients with choroidal neovascular membrane (CNVM) – 65 unilateral and 17 bilateral macular lesions – were enrolled. RAPD was assessed with an automated pupillometer and macular lesions evaluated with optical coherence tomography (OCT). The length of the ellipsoid zone disruption was measured as the longest length of lesion on the horizontal raster scans and the area of macular lesion was measured manually, mapping the affected area of ellipsoid zone on the enface images. Results: RAPD scores showed good correlation with the intereye difference in length of maximum ellipsoid zone disruption (r-value = 0.84, P value
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje