Pseudoprogression of Malignant Peripheral Nerve Sheath Tumor in Patient with Neurofibromatosis Type 1, a Case Report

Autor:	Andrés J. Lessing, Gregory M. Cote, Thomas F. DeLaney, Scott R. Plotkin, Kevin A. Raskin, Juan N. Lessing
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	malignant peripheral nerve sheath tumors pseudoprogression neurofibromatosis nerve tumor mri Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Case Reports in Oncology, Vol 14, Iss 3, Pp 1342-1346 (2021)
Druh dokumentu:	article
ISSN:	1662-6575
DOI:	10.1159/000518317
Popis:	Pseudoprogression, defined as the radiographic false appearance of disease progression, is not frequently observed in patients with malignant peripheral nerve sheath tumor (MPNST). We report on a case of a patient with neurofibromatosis type 1 (NF1) MPNST pseudoprogression that presented as suspected local recurrence 9.5 years after last treatment. The patient underwent surgical resection following growth of a mass on sequential MRI imaging; surgical pathology, however, showed skeletal muscle with atrophy, fibroadipose tissue, and fat necrosis, without any evidence of tumor. As MPNST survival rates increase, physicians should consider pseudoprogression as a potential presentation after prior treatment.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7e36e9d8017f4ff0904af119de87870b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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